This will affect your next synthesis attempt. Waiting will cancel the effect. Gives a bonus to quality gain while decreasing your chance of success. Prior to the first major crafting changes this ability could cause you to gain over 100 quality with one careful (bold) synthesis. Since the crafting changes I have noticed a significantly decreased effect.
I theorize it is more effective to use this ability in conjunction with Standard or Rapid Synthesis which already begin with lower quality gains.
Obtained automatically upon reaching Alchemist Rank 30.