Someone linked me to a guide a long time ago that was exactly what you are looking for...unfortunately I can't think of it.
My biggest suggestion is to drop Complex Shader Distance as low as it goes, that is the biggest system hog if I recall correctly.
Also using lower texture and model packages will greatly speed everything up, but then again that makes the game look horrid.
edit:BAM
http://eqiiforums.station.sony.com/eq2/board/message?board.id=tech_support&message.id=3265
That is the thread in all it's glory.
Edited, Dec 21st 2006 10:50pm by Lamnethx